iKnow

Quantitative Evaluation of P16ink4a Promoter Methylation Using Pyrosequencing in De Novo Diffuse Large b-Cell Lymphoma
Research Output | Dar Al-hikmah Library | IIUM Only

The p16INK4a tumor suppressor gene can be inactivated by a variety of events including promoter hypermethylation. In diffuse large B-cell lymphoma (DLBCL), p16INK4a methylation has been associated with advanced disease stage and higher IPI. The prognostic impact of p16INK4a methylation in DLBCL remains unclear; however, it has been suggested to cor

Experimental Studies of Position Control of Linkage Based Robotic Finger
Research Output | Dar Al-hikmah Library | IIUM Only

The experimental study of position control of a light weight and small size robotic finger during non-contact motion is presented in this paper. The finger possesses fingertip pinching and self adaptive grasping capabilities, and is made of a seven bar linkage mechanism with a slider in the middle phalanx. The control system is tested under the Pro

Assessing Interaction Quality in Arabic Online Discussion Forums
Research Output | Dar Al-hikmah Library | IIUM Only

This paper reports on a study, based on an extensive review of current literature in related areas, as a way forward in looking at the assessment of quality in Arabic online discussion forums (AODF). The paper will assess the interaction quality in AODF based on the criteria introduced by Henri (1992), Newman et al. (1996) and Garrison et al. (2001

Tp53 Mutations are Infrequent in Newly Diagnosed Chronic Lymphocytic Leukimia
Research Output | Dar Al-hikmah Library | IIUM Only

TP53 mutations in the absence of 17p-deletion correlate with rapid disease progression and poor survival in chronic lymphocytic leukemia (CLL). Herein, we determined the TP53 mutation frequency in 268 newly diagnosed CLL patients from a population-based material. Overall, we detected TP53 mutations in 3.7% of patients (n = 10), where 7/10 cases sho

Tp53 Mutations are Infrequent in Newly Diagnosed Chronic Lymphocytic Leukimia
Research Output | Dar Al-hikmah Library | IIUM Only

TP53 mutations in the absence of 17p-deletion correlate with rapid disease progression and poor survival in chronic lymphocytic leukemia (CLL). Herein, we determined the TP53 mutation frequency in 268 newly diagnosed CLL patients from a population-based material. Overall, we detected TP53 mutations in 3.7% of patients (n = 10), where 7/10 cases sho

Production of Sugar by Hydrolysis of Empty Fruit Bunches Using Palm Oil Mill Effluent (Pome) Based Cellulases: Optimization Study
Research Output | Dar Al-hikmah Library | IIUM Only

The utilization of lignocellulosic materials such as empty fruit bunches (EFB) from palm oil plant for bioethanol production attract increasing attention as an abundantly available and cheap renewable residue, especially in Malaysia where palm oil production is the major agricultural industry. The most challenging part in conversion of lignocellulo

non-Arabic Students’ Reading Preferences for e-Learning Programs
Research Output | Dar Al-hikmah Library | IIUM Only

Non-Arabic students are increasingly depending on e-learning programs. Readability of e-learning programs text has been shown to be influenced by a number of typographical variables including text type and size, screen line length, white space, etc. therefore, it is very important to improve the reading efficiency and satisfaction. Combination of i

Speciation of Fast and Slow Biochemical Oxygen Demand
Research Output | Dar Al-hikmah Library | IIUM Only

Biochemical Oxygen Demand (BOD) is a critical constituent used to measure the strength of organic pollution in water. Although new methodologies for organic quantification such as the Chemical Oxygen Demand (COD), Total Organic Carbon (TOC) tests and respirometry methodology have been introduced, the BOD method for determining organic strength is s

Determinants of Internal Audit Contribution to Strategic Management: Malaysian Evidences
Research Output | Dar Al-hikmah Library | IIUM Only

This paper examines from agency perspective how internal audit experience, audit committee attributes, risk management and control systems influence internal audit contribution to strategic management. The study analysed data collected from 117 head of internal audit function in public listed companies on Bursa Malaysia. Internal audit experience,

A Simulation Based Fly Optimisation Algorithm for Swarms of Mini Autonomous Surface Vehicles Application
Research Output | Dar Al-hikmah Library | IIUM Only

Present paper intends to provide a detailed description of a new bio-inspired Metaheuristic Algorithm. Based on the detailed study of the Drosophila, the flowchart behaviour for the algorithm, code implementation, methodologies and simulation analysis, a novel Fly Optimization Algorithm (FOA) approach is presented. The optimal simulation parameters

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