Research Output | Dar Al-hikmah Library | IIUM Only
Excitatory amino acid transporter-2 (EAAT2) is the predominant glutamate transporter that helps in maintaining low extracellular glutamate levels in the brain. Defect in EAAT2 causes impaired clearance and accumulation of this excitatory neurotransmitter, leading to excitotoxicity and neuronal cell death. The cerebellum and striatum play an importa