Research Output | Dar Al-hikmah Library | IIUM Only
Introduction: The dopamine hypothesis of schizophrenia is based on the fact that hyper-dopaminergic state is involved in causing psychosis and antipsychotic drugs block the dopamine receptor. COMT regulates the homeostatic levels of neurotransmitter dopamine in the synapses and plays a role in the neurocognitive function. The dysregulation of dopam