Research Output | Dar Al-hikmah Library | IIUM Only
Familial adenomatous polyposis ( FAP ) accounts for about 1% of colorectal cases in the United States. FAP arises from the germline mutation of the adenomatous polyposis coli ( APC) gene located on chromosome 5Q21.In one third of cases it arises from spontaneous mutation and have no associated family history. As these polyps will progress to carcin