Research Output | Dar Al-hikmah Library | IIUM Only
Non-erosive reflux disease (NERD) is the most common phenotype of gastro esophageal reflux disease (GERD). Dilated intercellular spaces (DIS) in prickle cell layers are considered as early signs of acid damage to the esophageal epithelium. Objectives: The objective of this study was to explore DIS in both superficial and prickle cell layer of the e