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Phytochemical, Pharmacological Activity and Molecular Docking Investigations of Tetracera Indica (Christm. & Panz.) Merr., Averrhoa Bilimbi Linn. and Gymnanthemum Glaberrimum (Welw. Ex O.hoffm) H. Rob
Knowledge Resources | Dar Al-hikmah Library | Public Access

Subject(s): Dissertations, Academic -- Kulliyyah of Pharmacy -- IIUM Summary: Tetracera indica and Averrhoa bilimbi are used in traditional treatment of diabetes mellitus while Gymnanthemum glaberrimum is used as a remedy for skin cancer. The objectives of the present study were to investigate the pharmacological activity of leaves of T. indica

Dry Eye and Visual Function in Young Adult Diabetics
Knowledge Resources | Dar Al-hikmah Library | Public Access

Subject(s): Dissertations, Academic -- Department of Optometry and Visual Science -- IIUM Summary: The escalating prevalence of diabetes in the world, and in Malaysia particularly is a concern. Limited studies have linked the dry eye status in the young adult diabetic population using standardised questionnaire with standard tear film function

Reflective Practice in Medical Imaging Education
Knowledge Resources | Dar Al-hikmah Library | Public Access

Subject(s): Dissertations, Academic -- Department of Diagnostic Imaging and Radiotherapy -- IIUM Summary: Although reflective practice has been implemented in many medical sciences programmes, namely the Medical Programme, the use of this method of teaching-learning is found to be lacking in Medical imaging Education. Published studies related

Brain Derived Neurotropic Factor (Bndf) Dna Methylation in Schizophrenia and its Association with Antipsychotic Use
Knowledge Resources | Dar Al-hikmah Library | Public Access

Subject(s): Dissertations, Academic -- Department of Basic Medical Sciences -- IIUM Summary: Epigenetic mechanisms regulate gene functions without causing a change in the nucleotide sequence of DNA. Brain-derived neurotrophic factor (BDNF) is a neurotrophin that regulates synaptic transmission, plasticity and has essential role in neurodevelopm

The Calcaneal Morphology Study in Malay Population in Pahang
Knowledge Resources | Dar Al-hikmah Library | Public Access

Subject(s): Dissertations, Academic -- Department of Orthopaedics,Traumatology & Rehabilitation -- IIUM Summary: The calcaneus is a unique bone of the foot and it serves various important roles and functions for from at various stages of human locomotion. Simple stance phase to heel strike requires the calcaneum to be in its perfect anatomi

Development, Characterization and Pharmacokinetic Evaluation of raloxifene-Loaded Transfersomes and Ethosomes for Transdermal Delivery
Knowledge Resources | Dar Al-hikmah Library | Public Access

Subject(s): Dissertations, Academic -- Kulliyyah of Pharmacy -- IIUM Summary: Raloxifene HCl is a second generation selective estrogen receptor modulator (SERM), used primarily in osteoporosis and also finds a potential use in invasive breast cancer. This drug has a poor bioavailability, which is limited to only 2%. This study aims to develop l

Synthesis and Computational Studies of sydnone-Based Derivatives as Potential anti-Inflammatory Agents
Knowledge Resources | Dar Al-hikmah Library | Public Access

Subject(s): Dissertations, Academic -- Kulliyyah of Pharmacy -- IIUM Summary: Various literature sources have documented that sydnones are important bioactive molecules with a wide spectrum of activities involving the anti-proliferative and anti-inflammatory actions. Phenyl styrylketones and their derivatives as members of the chalcone family h

Development, Characterization and Pharmacokinetic Study of Solid Dispersion Formulation of Telmisartan
Knowledge Resources | Dar Al-hikmah Library | Public Access

Subject(s): Dissertations, Academic -- Department of Pharmaceutical Technology -- IIUM Summary: The drugs that belong to class II of Biopharmaceutical Classification System face several challenges in their dissolution and bioavailability due to their poor water solubility. Solid dispersion is an effective method to enhance the solubility of poo

Bioassay Guided Isolation and Characterization of Compounds with Antioxidant Activities from the Leaves of Entada Spiralis Ridl. (Sintok)
Knowledge Resources | Dar Al-hikmah Library | Public Access

Subject(s): Dissertations, Academic -- Department of Pharmaceutical Chemistry -- IIUM Summary: Entada spiralis Ridl. known as Sintok or Akar Beluru is the woody climber plant belong to Leguminoceae family. E. spiralis is an excellent foaming agent due to the presence of saponin. Thus, E. spiralis stem bark is established used as natural body so

Apoptosis Activities of Nickel and Copper Complexes from Thymoquinone and Dithiocarbamate on Oral Cancer Cell Lines in Vitro
Knowledge Resources | Dar Al-hikmah Library | Public Access

Subject(s): Dissertations, Academic -- Kulliyyah of Pharmacy -- IIUM Summary: Oral squamous cell carcinoma (OSCC) has been associated with high morbidity and mortality rate. Metal-based anticancer drugs such as platinum-based agents have been widely used to treat various cancer cells including OSCC. However, their efficiency is limited by the s

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