Research Output | Dar Al-hikmah Library | IIUM Only
1. Introduction 1.1 Methadone and methadone maintenance therapy (MMT): An overview Methadone acts on the opioid receptors and produces many of the same effects of morphine and heroin. In the treatment of opioid dependence, methadone has cross-tolerance with other opioid, including heroin and morphine and a long duration of effect. Higher doses of m