Research Output | Dar Al-hikmah Library | IIUM Only
PRDM9 is a human zinc finger (ZF) gene responsible for initiating much or all of human recombination. PRDM9 shows extreme variation in both number and sequence of its ZFs, between species and amongst individuals, across mammals. The commonest PRDM9 allele binds the human hotspot motif, CCNCCNTNNCCNC, but other human alleles bind different targets.