Although over 90 independent risk variants have been identified for Parkinson's disease using genome-wide association studies, most studies have been performed in just one population at a time. Here we performed a large-scale multi-ancestry meta-analysis of Parkinson's disease with 49,049 cases, 18,785 proxy cases and 2,458,063 controls inc

This study investigates the design of a stirred batch reactor with scale-up for the degumming of crude palm oil (CPO) using phosphoric acid (H3PO4). Laboratory-scale experiments were conducted in a triple-neck round vessel, followed by a scale-up to a larger-scale flat-bottom stirred tank reactor. Traditional scale-up methods using geometric simila

Objective: The main aim of this research was to evaluate the effect of mixed herbs on blood HbA1c, and the liver function tests in type 2 diabetes mellitus (T2DM) patients. Methods: This was a quasi-experimental design where no comparison was made with either placebo or control. We examined the effect of herbs namely, coriander leaves (Coriandrum s

Frank–Ter Haar syndrome (FTHS) is a rare genetic hereditary autosomal recessive disorder characterized by defective malformation of cardiovascular, craniofacial, and skeletal system. Mutations in the SH3PXD2B gene are a common cause in the development of FTHS. We recruited a family with two affected individuals (3-year-old female and 2-month-old

In the recent technology development, fuel cell has been widely used in many applications, including transportation and industry. Platinum catalysts are used to catalyst the reaction at the oxygen electrode, but they are expensive and has limited supply. A nickel-boron nanoparticle catalyst is proposed as a substitute for fuel cell catalyst materia

(ISSN 1985-2533 / 2232-111X) is the official publication of the Malaysian Orthopaedic Association (MOA) and the ASEAN Orthopaedic Association (AOA). In May 2007, MOA published the first standalone issue of MOJ with the aim of disseminating new knowledge and providing updates in orthopaedics, trauma and musculoskeletal research. Since then, MOJ has

Cantigi extract exhibit numerous activities, including antioxidants. Various dosage forms have been developed, except a capsule formulation. Capsule formulation offers numerous advantages. Objectives: To prepare and characterize the cantigi extract, extract-loaded nanoparticles, capsules containing extract, and capsules containing nanoparticles as

Kenaf composites have a high strength-to-weight ratio, but weak fiber-matrix interface bonding limits their automotive use. To address this, a novel technique was developed to fabricate multiphase composites using graphene nanoplatelets (GNPs), kenaf fibers, and an epoxy matrix. The composites were made using vacuum infusion molding, with the GNPs

In recent years, cloud computing has become an essential distributed computing platform and has achieved enormous popularity. Within cloud computing, the Cloud service broker creates an abstraction layer between provider and consumer so that customers notice the cloud service providers’ offered services’ solitary view. The brokers of cloud serv

This study assesses the effect of rib size, shape, and location in a suddenly expanded flow at sonic Mach number. Flow from a converging nozzle is exhausted into a larger area of duct diameter of 18 mm. The geometric parameters considered are the area ratio, duct length, rib radius, and inertia parameters, which are considered the level of expansio