PAD4 catalyses the conversion of peptidylarginine into peptidylcitrulline. Overexpression of PAD4 and the peptidylcitrulline products have been reported in various diseases including rheumatoid arthritis and cancers. GSK199 is the first PAD4 selective reversible inhibitor discovered. The impact of GSK199 binding on PAD4 stability and flexibility, h
Concrete 101
Knowledge Resources | Dar Al-hikmah Library | Public Access
Subject(s): Concrete construction
Subject: This basic concrete technology CD-ROM covers the ingredients of concrete, proportioning of concrete, safety practices to follow when working with concrete, and placement and finishing practices. It is intended as a general overview for individuals with no prior experience in concrete. The CD-ROM includ
Motorcycling culture is often framed as consisting of outlaws, while being predominantly a male arena, in which bikers are always assumed to be masculine. It is often assumed that women’s roles in motorcycling culture are relegated to the status of ‘bystander,’ where they exist within the community as a support to their male partners and fami
