Research Output | Dar Al-hikmah Library | IIUM Only
Streptococcus pneumoniae, a major human pathogen causing meningitis, pneumonia and bacteraemia produces hyaluronidase as its virulence factor. This enzyme increases the bacterial permeability to the host tissue by degrading hyaluronic acids that maintain the viscosity of connective tissues. Limited hyaluronidase inhibitors are available at the mome