CYP2D6 plays a major role in the metabolism of tamoxifen, and polymorphism of Pglycoprotein has been associated with resistance of many drug therapies. This study investigates the clinical impact of genetic variants of CYP2D6 and ABCB1 in breast cancer patients treated with tamoxifen. Blood samples from 95 breast cancer patients treated with tamoxi

This research explores preliminarily the practices of quality management, management commitment in quality management, and quality management implementation problems in construction projects in the context of Malaysian construction industry. The research applies semi-structured interview approach with twelve project management practitioners. The fi

This paper discusses an extension of analytic hierarchy process which is adopted in fuzzy set theory for multi-criteria decision-making purposes. This method is utilised to overcome the fuzziness problem of the initial input data-sets using the concept of membership degree. The advantage of the proposed approach is applied in the hypothetical examp

Microwave processing ceramics is emerging fast as a new field of ceramic processing and material synthesis. The past year has witnessed significant progress in the aspects of commercialization and application of the technology to new areas. Further research states that Titanium Carbide (TiC) is the best cutting tool due to its high melting point an

Gas flow measurement is required in numerous applications; particularly in oil, and gas, nuclear energy, chemical proccssing illdustrics including food, pharmaceutical indUSlryand in agricultural sectors. Gas flow occurs in heat el<changers, steam generators, chemical reactors, oil transportation and other process equipment items. Hence the imp

The three basic circuit elements namely resistor (R), inductor (L) and capacitor are known to be passive discrete elements which are used as electronic components in signal conditioning and processing. An inductor or capacitor is an energy storage device. Capacitor's current or an inductor's voltage does not change instantaneously. Ideally

An understanding of bus service disparities between urban and rural settlements is necessary to provide the best approach to improving and providing an efficient public transportation system in the country. An efficient public transportation system will contribute towards sustainable economic growth and healthy social development of the district, w

Effectiveness of active control of micro jets has been examined by conducting experiments through an abruptly expanded axi-symmetric duct in a view to control base pressure. For this purpose, 1mm orifice diameter micro jets have been deployed at an interval of 900 along the exit diameter of the nozzle. The experiments have been conducted by conside

Society has undergone massive changes in its socioeconomic and cultural facets. Thus the concept of knowledge society has got momentum with it, with education being a key motivator of these changes. Following the introduction of the “Wawasan 2020” (Vision 2020) and the subsequent declaration of the Transformasi Nasional (TN50) policy, increasin

The present experimental evaluation deals with the behavior of base pressure (BP) in a suddenly expanded duct at supersonic Mach number regimes. The experiments have been conducted for two cases viz. Without and with the use of microjets or active control. The plan of experiments was planned as per the Taguchi design of experiments for acquiring da