Research Output | Dar Al-hikmah Library | IIUM Only | Google Scholar
Hexokinase isoform 2 (HK2) is a rate-limiting enzyme that catalyses the phosphorylation of glucose into glucose-6-phosphate (G6P) in the first step of glycolysis. In cancer cells, HK2 is highly expressed to meet the increased energy demand for rapid proliferation. This overexpression makes HK2 an attractive target fordrugdevelopment. Nevertheless,