Research Output | Dar Al-hikmah Library | IIUM Only
A modified release gliclazide 60 mg tablet using Methocel® K100 Premium LV DC2 as a drug retaining polymer was prepared by direct compression. Central composite design was adopted for formulation optimization. The two independent formulation variables included the amount of Methocel® K100 LV DC2 and Maltrin® M150, whereas the response variables