Protein arginine deiminase IV (PAD4) is a potential target for diseases including rheumatoid arthritis and cancers. Currently, GSK199 is a potent, selective yet reversible PAD4 inhibitor. Its derivative, GSK106, on the other hand, was reported as an inactive compound when tested against PAD4 assay. Although they had similar skeleton, their impact t

Cancer which synonymously known as neoplasia is a genetic disorder of cell growth that is triggered by acquired or less commonly inherited mutations affecting a single cell and its clonal progeny. The aims of this scoping review was to investigate the role of sugar and sugar substitutes in breast, lung, and oral cancers with a hypothesis that sugar

Serba Dinamik has been listed a couple of years ago and achieved tremendous growth in financial performance. The business expansion across different regions around the world has boosted the market value of the company. However, in the financial year audit ended 2020, several audit issues highlighted by the auditor have created a wave in the industr

Introduction: In Malaysia, one in three citizens suffers from mental health problems. According to Department of Statistic Malaysia (DOSM), the ageing population increased from 5% in 2010 to 6.8% in 2020. As the ageing population increasing, the burden of disease and their mental health literacy is a challenge. The Mental SEHAT module, embedded in

Ethics, science, and policy are three different worlds, but they must collaborate closely to address the wicked problems of our age. Today we face various ethical challenges in the field of sciences and technology which cannot be solved without holistic ethical science guidelines and policies. This handbook puts together the guiding principles and

Introduction: The purpose of this study was to review the significance of oesophago-gastroduodenoscopy (OGD) findings in patients with dyspepsia but without alarm features. Materials and Methods: OGD data from January 2017 to December 2017 were collected from ipesakit. The demographic details, indications and findings were reviewed. Results: OGDs w

Entrepreneurship Education provides the opportunities and the training that would enable graduates to be creative thinkers—those with innovative business management skills, strong self-esteem, and the kind of discipline that would ultimately allow them to start their own businesses and create jobs for others. Nonetheless, studies have also shown

This article explores HAMKA‘s (d. 1981) approach in his interpretation of Qur‘anic verses on Christianity in his Tafsīr al-Azhar. HAMKA produces many literary works. Tafsīr al-Azhar is HAMKA‘s magnum opus produced in Malay language. As a scholar and social activist, HAMKA‘s Qur‘anic exegesis embedded a broad range of contextualized loca

The quality of air conditioning and ventilation systems in laboratories is vital to ensure optimum health of the users and guarantee the accuracy of experiments conducted. Moreover, recent studies show that the average quality of air conditioning and ventilation systems in labs can pose health risks to occupants. The study aims to examine the relat

This research aimed to investigate the different effects of fertilization (through the use of vermicompost and chemical fertilizer) on carotenoid composition as well as the chlorophyll content in Clinacanthus nutans Lindau. A field study employing a Randomized Complete Block Design (RCBD) was conducted on four treatment groups; control plants that