Research Output | Dar Al-hikmah Library | IIUM Only
Dilated spaces at intercellular junctions (DIS) in prickle cell layers are considered as early signs of acid-initiated damage to these esophageal epithelium. In order to enter the mucosal intercellular spaces, acid and pepsin have to penetrate the intercellular adhesion sites of the most superficial epithelial cells. The aim of this study is to exp