Purpose: To identify the structural requirements for designing a lead key for insulin-like growth factor (IGF-1R) inhibition using group-based quantitative structure activity relationship (GQSAR) and molecular docking. Methods: GQSAR method requires fragmentation of molecules. The molecules in the current dataset were fragmented into three (R1, R2

Stevia rebaudiana bertoni produces sweet glycosides with zero calorie and has strong health and dietary implications. With these properties, it has the potential to substitute sugar. However, poor seed germination in this plant constitute obstacle towards large scale propagation, thereby causing plant materials to be scarce and costly. High percent

This paper presents stability analysis and vibration control of a class of negative imaginary systems. A flexible manipulator that moves in a horizontal plane is considered and is modelled using the finite element method. The system with two poles at the origin is shown to possess negative imaginary properties. Subsequently, an integral resonant co

Metal matrix composites are attractive light weight materials with potential attributes to substitute automotive materials without sacrifing performance. This present study aims to investigate the wear characteristics of aluminium (Al) 6061 reinforced with silicon carbide particles (SiCp) of three (3) different particle sizes. The reinforcement con

Design of rectangular microstrip patch antenna (RMPA) using stepped cut at four corners for broadband/multiband application is presented in this paper. Stepped cut at four corner technique is used in order to increase the bandwidth and gain of the antenna. Design and simulation of Modified rectangular microstrip patch antenna are done by CST Microw

Orifice meter is a flow measuring device which is widely used in various industrial applications. Although the device gives accurate measurement during steady flow, measurement errors related to square root and sampling errors are unavoidable if pulsations exist. This research investigatesand improves the performance of an orifice plate flow meter

Human worldwide are exposed to arsenic mainly through drinking of arsenic-contaminated ground water. Arsenic is one of the environmental toxins reported to be associated with atherosclerosis with more attention given to inorganic arsenic as it was thought to be more toxic. Since organic arsenic particularly monosodium methylarsonate are still popul

The aim of this paper is to explore the Islamic law of muamalat as the tools of consumer protection in dealings with exclusion clauses. The underlying philosophy under the Malaysian law is that consumers are free to enter into contracts and therefore must take care of their own interest. This principle, which is based on the assumption of equal bar

Purpose – The business world metaphorically has turned flat for the onslaught of globalization. The ultimate purpose for achieving business success is a common anticipation for all types of businesses, particularly small businesses that are thought as a nucleus of the business world. The purpose of this research is to assess the mediating relatio

The business world metaphorically has turned flat for the onslaught of globalization. The ultimate purpose of achieving business success is a common anticipation for all types of businesses, particularly small businesses that are thought as a nucleus of the business world. The purpose of this research is to assess the mediating relationship of fina