Introduction: Methylation of promoter region of p16 leading to gene silencing has been implicated in a wide range of malignancies including lymphomas. In diffuse large B cell lymphoma (DLBCL) particularly, a varying percentage of epigenetic inactivation of p16 promoter region was observed ranging from 16 - 54%. However, quantitative analysis of p16

Introduction: Epigenetic methylation has been implicated in the pathogenesis of diffuse large B cell lymphoma (DLBCL). This study investigated the methylation status of p16, MGMT and SPOCK2. Aberrantly methylated p16 and MGMT have been linked to DLBCL, but not SPOCK2. p16 inhibits cyclin-dependent kinase, which results in retinoblastoma phosphoryla

This study examined how well the Bilingual Virtual Toolkit (BVT) Let's Twist tool, used in an online Moodle learning environment, addressed pronunciation issues among English and Malay second language learners at Al-Saadah Complex. 18 students' pronunciation abilities were evaluated using a pre-test/post-test design; via qualitative action

Background: The ramifications of immobilisation manifest in a spectrum of physical and mental complications across participants demographics, irrespective of age. The resultant challenges impede individuals from independently executing routine activities, such as bathing and mobility. Consequently, there is an escalating demand for nursing care to

Background: Prematurely born, low birth weight, or sick infants are vulnerable and often do not receive enough breast milk from their mothers. In such cases, donated breast milk from other mothers can be safely stored in a milk bank. However, some Muslim countries have been hesitant to establish milk banks due to religious and ethical concerns. Des

The paper "Harmonizing Lifelong Learning with Islamic Values: A Framework for Personal and Societal Development" explores the integration of lifelong learning with Islamic principles to address the challenges posed by modernity and digital globalization. It emphasizes the significance of grounding lifelong learning in Islamic ethics to fost

Lavidge and Steiner’s (1961) hierarchy of effects model has strengths in its pragmatism and clarity. It outlines the series of steps consumers take with the purchase of products being the final step. The steps are related to the cognitive, affective and conative components of psychology. Advertisers could use advertising and other marketing commu

This examination presents a unique fusion of Environmental Impact Assessment (EIA) and Life Cycle Assessment (LCA) methodologies, aimed at cultivating a Toyyib environment. This concept, embedded in Islamic ethical principles, refers to an ecologically pure and morally sound setting. The paper focuses on sustainable practices in managing natural el

Somalia has a relatively small amount of forested land, covering only about 10.5% of the nation’s total land area. The reason for this is that much of the country’s tropical forests, which were originally located along the Shabelle and Jubba rivers reclaimed agricultural land. This study examines the relationship between environmental degradati

The design for UAV was planned taking into account the real-life engineering problems such as different phases involved in developing a product. Here the task is to design, create, build and test a remote-control airplane. The planning and designing of an aircraft must start from the scratch, with lots of restrictions and parameters, like a specifi