Introduction: X-linked Alport syndrome (OMIM 301050) is caused by COL4A5 missense variants in 40% of families. This study examined the effects of chemical chaperone treatment (sodium 4-phenylbutyrate) on fibroblast cell lines derived from men with missense mutations. Methods: Dermal fibroblast cultures were established from 2 affected men and 3 nor

This study aims to investigate the mediating effect of communication power on the relationships between mentoring and career success. It also tests the moderating effects of proactive personality and self-efficacy in the model. The study employs a quantitative research design, using survey method with questionnaire as the instrument for data collec

Consumption of meat from halal (lawful) sources is essential for Muslims. The identification of non-halal meat is one of the main issues that face consumers in meat markets, especially in non-Islamic countries. Pig is one of the non-halal sources of meat, and hence pig meat and its derivatives are forbidden for Muslims to consume. Although several

The kappa opioid receptor (KOR) system has been linked to many types of drug addiction. An upregulation of the KOR leads to negative reinforcement effects which might contribute to drug relapse. Previously, our study has shown that a treatment combination of 0.3 mg/kg buprenorphine and 1.0 mg/kg methamphetamine (a partial nociceptin opioid peptide

A search for invisible decays of a Higgs boson is performed using proton-proton collision data collected with the CMS detector at the LHC in 2016 at a center-of-mass energy , corresponding to an integrated luminosity of 35.9. The search targets the production of a Higgs boson via vector boson fusion. The data are found to be in agreement with the b

Measurements of normalized differential cross sections as functions of the multiplicity and kinematic variables of charged-particle tracks from the underlying event in top quark and antiquark pair production are presented. The measurements are performed in proton-proton collisions at a center-of-mass energy of 13 TeV, and are based on data collecte

A search is presented for charged Higgs bosons in the H± → τ ± ντ decay mode in the hadronic final state and in final states with an electron or a muon. The search is based on proton-proton collision data recorded by the CMS experiment in 2016 at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb−1 . Th

A search is presented for pair production of the standard model Higgs boson using data from proton-proton collisions at a centre-of-mass energy of 13 TeV, collected by the CMS experiment at the CERN LHC in 2016, and corresponding to an integrated luminosity of 35.9 fb−1 . The final state consists of two b quark-antiquark pairs. The search is cond

The χb1ð3PÞ and χb2ð3PÞ states are observed through their ϒð3SÞγ decays, using an event sample of proton-proton collisions collected by the CMS experiment at the CERN LHC. The data were collected at a center-of-mass energy of 13 TeV and correspond to an integrated luminosity of 80.0 fb−1. The ϒð3SÞ mesons are identified through their

The leaves of Neolamarckia cadamba (NC) (Roxb.) Bosser (family: Rubiaceae) aretraditionally used to treat breast cancer in Malaysia; however, this traditional claim is yet to be scientifically verified. Hence, this study was aimed to evaluate the anticancer effect of NC leaves’ ethanol extract against breast cancer cell line (MCF-7 cells) using a